Sodium/glucose cotransporter 2 and renoprotection: From the perspective of energy regulation and water conservation
Sodium/glucose cotransporter 2 (SGLT2) is a renal low-affinity high-capacity sodium/glucose cotransporter expressed in the apical membrane of the early segment of proximal tubules. SGLT2 reabsorbs filtered glucose in the kidney, and its inhibitors represent a new class of oral medications used for t...
Main Authors: | Kento Kitada, Satoshi Kidoguchi, Daisuke Nakano, Akira Nishiyama |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-11-01
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Series: | Journal of Pharmacological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861321000736 |
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