Small extracellular vesicles ameliorate peripheral neuropathy and enhance chemotherapy of oxaliplatin on ovarian cancer

Small extracellular vesicles ameliorate peripheral neuropathy and enhance chemotherapy of oxaliplatin on ovarian cancer

Abstract There are no effective treatments for chemotherapy induced peripheral neuropathy (CIPN). Small extracellular vesicles (sEVs) facilitate intercellular communication and mediate nerve function and tumour progression. We found that the treatment of mice bearing ovarian tumour with sEVs derived...

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Bibliographic Details
Main Authors: Yi Zhang, Chao Li, Yi Qin, Pasquale Cepparulo, Michael Millman, Michael Chopp, Amy Kemper, Alexandra Szalad, Xuerong Lu, Lei Wang, Zheng Gang Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-03-01
Series:Journal of Extracellular Vesicles
Subjects:
Chemotherapy‐induced peripheral neuropathy
microRNAs
ovarian cancer
small extracellular vesicles
Online Access:https://doi.org/10.1002/jev2.12073

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