Regional balance between glutamate+glutamine and GABA+ in the resting human brain

Regional balance between glutamate+glutamine and GABA+ in the resting human brain

Models of healthy brain function and psychiatric conditions assume that excitatory and inhibitory activity are balanced in the human brain at multiple spatial and temporal scales. In human neuroimaging, concentrations of the major excitatory (glutamate) and inhibitory (γ-aminobutyric acid, GABA) neu...

Full description

Bibliographic Details
Main Authors:	Adam Steel, Mark Mikkelsen, Richard A.E. Edden, Caroline E. Robertson
Format:	Article
Language:	English
Published:	Elsevier 2020-10-01
Series:	NeuroImage
Subjects:	GABA Glutamate MRS Excitation Inhibition
Online Access:	http://www.sciencedirect.com/science/article/pii/S105381192030598X

Similar Items

Simultaneous quantification of GABA, Glx and GSH in the neonatal human brain using magnetic resonance spectroscopy
by: Yanez Lopez Maria, et al.
Published: (2021-06-01)

Effects of repetitive TMS of the motor cortex on disease progression and on glutamate and GABA levels in ALS: A proof of principle study
by: Vincenzo Di Lazzaro, et al.
Published: (2017-09-01)

GABA and glutamate in schizophrenia: A 7 T 1H-MRS study
by: Anouk Marsman, et al.
Published: (2014-01-01)

GABA-A and NMDA receptor expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics.
by: Amol K Bhandage, et al.
Published: (2014-12-01)

GABA Levels in Left and Right Sensorimotor Cortex Correlate across Individuals
by: Nicolaas A. J. Puts, et al.
Published: (2018-07-01)

Brain GABA+ changes in primary hypothyroidism patients before and after levothyroxine treatment: A longitudinal magnetic resonance spectroscopy study
by: Bo Liu, et al.
Published: (2020-01-01)

GABA levels are differentially associated with bimanual motor performance in older as compared to young adults
by: Celine Maes, et al.
Published: (2021-05-01)

Acute Alcohol Effects on Response Inhibition Depend on Response Automatization, but not on GABA or Glutamate Levels in the ACC and Striatum
by: Wiebke Bensmann, et al.
Published: (2020-02-01)

The amino acid transporters of the glutamate/GABA-glutamine cycle and their impact on insulin and glucagon secretion
by: Monica eJenstad, et al.
Published: (2013-12-01)

Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models
by: Cheryl L Gatto, et al.
Published: (2010-06-01)

Simultaneous Measurement of the BOLD Effect and Metabolic Changes in Response to Visual Stimulation Using the MEGA-PRESS Sequence at 3 T
by: Gerard Eric Dwyer, et al.
Published: (2021-03-01)

The glutamate-glutamine(GABA) cycle: importance of late postnatal development and potential reciprocal interactions between biosynthesis and degradation
by: Leif eHertz
Published: (2013-05-01)

Task-related measures of short-interval intracortical inhibition and GABA levels in healthy young and older adults: A multimodal TMS-MRS study
by: K. Cuypers, et al.
Published: (2020-03-01)

Intelligence and Brain Efficiency: Investigating the Association between Working Memory Performance, Glutamate, and GABA
by: Anouk Marsman, et al.
Published: (2017-09-01)

Glutamate and GABA in appetite regulation
by: Teresa Cardoso Delgado
Published: (2013-08-01)

Glutamate and GABA transporters in brain
by: Yun eZhou, et al.
Published: (2013-11-01)

Brain MR Spectroscopy in Autism Spectrum Disorder- the GABA excitatory/inhibitory imbalance theory revisited
by: Maiken Kirkegaard Brix, et al.
Published: (2015-06-01)

Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents
by: Julia E. Cohen-Gilbert, et al.
Published: (2015-12-01)

ASTROCYTIC CONTROL OF BIOSYNTHESIS AND TURNOVER OF THE NEUROTRANSMITTERS GLUTAMATE AND GABA
by: Arne eSchousboe, et al.
Published: (2013-08-01)

The effect of transcranial direct current stimulation: a role for cortical excitation/inhibition balance?
by: Beatrix eKrause, et al.
Published: (2013-09-01)

Inhibition of NMDA receptors by agmatine is followed by GABA/glutamate balance in benzodiazepine withdrawal syndrome
by: Hira Rafi, et al.
Published: (2021-07-01)

Cortisol decreases prefrontal glutamine concentrations
by: Bhardwaj, Paramjit Paul
Published: (2009)

Effects of SSRI treatment on GABA and glutamate levels in an associative relearning paradigm
by: B. Spurny, et al.
Published: (2021-05-01)

Control of cortical neuronal migration by glutamate and GABA
by: Heiko J Luhmann, et al.
Published: (2015-01-01)

Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model
by: Seika Takayanagi-Kiya, et al.
Published: (2016-07-01)

GABA and glutamate uptake and metabolism in retinal glial (Müller) cells
by: Andreas eBringmann, et al.
Published: (2013-04-01)

Glutamate and GABA Receptor-Mediated Plasticity in the Mesolimbic Dopamine System by Alcohol
by: Nelson, Ashley Cerise
Published: (2016)

Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression
by: Renae M. Ryan, et al.
Published: (2021-04-01)

Effects of Mutations in TSC Genes on Neurodevelopment and Synaptic Transmission
by: Davide Bassetti, et al.
Published: (2021-07-01)

Detection of Neurotransmitters in the Human Brain Using Magnetic Resonance Spectroscopy
by: Tapper, Sofie
Published: (2013)

Associations between sensory processing and electrophysiological and neurochemical measures in children with ASD: an EEG-MRS study
by: Sarah Pierce, et al.
Published: (2021-01-01)

Automated ROI-Based Labeling for Multi-Voxel Magnetic Resonance Spectroscopy Data Using FreeSurfer
by: Benjamin Spurny, et al.
Published: (2019-02-01)

Chronic Stress in a Rat Model of Depression Disturbs the Glutamine–Glutamate–GABA Cycle in the Striatum, Hippocampus, and Cerebellum
by: Xu S, et al.
Published: (2020-02-01)

Gamma-aminobutyric acid and glutamic acid levels in the auditory pathway of rats with chronic tinnitus: A direct determination using high resolution point-resolved proton magnetic resonance spectroscopy (1H-MRS)
by: Thomas J Brozoski, et al.
Published: (2012-02-01)

Prefrontal cortical alterations of glutamate and GABA neurotransmission in schizophrenia: Insights for rational biomarker development
by: Kirsten E. Schoonover, et al.
Published: (2020-12-01)

GABA Concentrations in the Anterior Cingulate Cortex Are Associated with Fear Network Function and Fear Recovery in Humans
by: Nina Levar, et al.
Published: (2017-04-01)

Glutamate, Glutamine and GABA Levels in Rat Brain Measured Using MRS, HPLC and NMR Methods in Study of Two Models of Autism
by: Elzbieta Zieminska, et al.
Published: (2018-11-01)

Inhibition of L-glutamate and GABA synaptosome uptake by crotoxin, the major neurotoxin from Crotalus durissus terrificus venom
by: A.L. Cecchini, et al.
Published: (2004-01-01)

Changes in GABA and Glutamate concentrations during Memory Tasks in Patients with Parkinson’s disease undergoing DBS Surgery
by: Robert J Buchanan, et al.
Published: (2014-03-01)

MRS of Brain Metabolite Levels Demonstrates the Ability of Scavenging of Excess Brain Glutamate to Protect against Nerve Agent Induced Seizures
by: Angela Ruban, et al.
Published: (2015-02-01)