Lipo-oxytocin-1, a Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-Lasting Effects on Anxiety-Related Behavior and Social Avoidance in CD157 Knockout Mice

Lipo-oxytocin-1, a Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-Lasting Effects on Anxiety-Related Behavior and Social Avoidance in CD157 Knockout Mice

Oxytocin (OT) is a nonapeptide hormone that is secreted into the brain and blood circulation. OT has not only classical neurohormonal roles in uterine contraction and milk ejection during the reproductive phase in females, but has also been shown to have new pivotal neuromodulatory roles in social r...

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Bibliographic Details
Main Authors: Akira Mizuno, Stanislav M. Cherepanov, Yusuke Kikuchi, Azam AKM Fakhrul, Shirin Akther, Kisaburo Deguchi, Toru Yoshihara, Katsuhiko Ishihara, Satoshi Shuto, Haruhiro Higashida
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Brain Sciences
Subjects:
synthetic oxytocin
oxytocin analog
lipidation
social behavior
social avoidance
autism
Bst1
CD157
Online Access:http://www.mdpi.com/2076-3425/5/1/3

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