Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study

Objectives End-of-life hospitalisations may not be associated with improved quality of life. Studies indicate differences in end-of-life care for cancer and non-cancer patients; however, data on hospital utilisation are sparse. This study aimed to compare end-of-life hospitalisation and place of dea...

Full description

Bibliographic Details
Main Authors: Mette Asbjoern Neergaard, Søren Paaske Johnsen, Henrik Nielsen, Anne Høy Seemann Vestergaard, Thomas Lyngaa, Kristina Grønborg Laut
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/6/e033493.full
id doaj-8da0d876e42a4697a3c00e6cfff74295
record_format Article
spelling doaj-8da0d876e42a4697a3c00e6cfff742952021-03-13T09:31:06ZengBMJ Publishing GroupBMJ Open2044-60552020-06-0110610.1136/bmjopen-2019-033493Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort studyMette Asbjoern Neergaard0Søren Paaske Johnsen1Henrik Nielsen2Anne Høy Seemann Vestergaard3Thomas Lyngaa4Kristina Grønborg Laut5The Palliative Care Team, Department of Oncology, Aarhus University Hospital, Aarhus, DenmarkDanish Center for Clinical Health Services Research, Aalborg University, Aalborg, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkObjectives End-of-life hospitalisations may not be associated with improved quality of life. Studies indicate differences in end-of-life care for cancer and non-cancer patients; however, data on hospital utilisation are sparse. This study aimed to compare end-of-life hospitalisation and place of death among patients dying from cancer, heart failure or chronic obstructive pulmonary disease (COPD).Design A nationwide register-based cohort study.Setting Data on all in-hospital admissions obtained from nationwide Danish medical registries.Participants All decedents dying from cancer, heart failure or COPD disease in Denmark between 2006 and 2015.Outcome measures Data on all in-hospital admissions within 6 months and 30 days before death as well as place of death. Comparisons were made according to cause of death while adjusting for age, sex, comorbidity, partner status and residential region.Results Among 154 235 decedents, the median total bed days in hospital within 6 months before death was 19 days for cancer patients, 10 days for patients with heart failure and 11 days for patients with COPD. Within 30 days before death, this was 9 days for cancer patients, and 6 days for patients with heart failure and COPD. Compared with cancer patients, the adjusted relative bed day use was 0.65 (95% CI, 0.63 to 0.68) for heart failure patients and 0.68 (95% CI, 0.66 to 0.69) for patients with COPD within 6 months before death. Correspondingly, this was 0.65 (95% CI, 0.63 to 0.68) and 0.70 (95% CI, 0.68 to 0.71) within 30 days before death.Patients had almost the same risk of dying in hospital independently of death cause (46.2% to 56.0%).Conclusion Patients with cancer, heart failure and COPD all spent considerable part of their end of life in hospital. Hospital use was highest among cancer patients; however, absolute differences were small.https://bmjopen.bmj.com/content/10/6/e033493.full
collection DOAJ
language English
format Article
sources DOAJ
author Mette Asbjoern Neergaard
Søren Paaske Johnsen
Henrik Nielsen
Anne Høy Seemann Vestergaard
Thomas Lyngaa
Kristina Grønborg Laut
spellingShingle Mette Asbjoern Neergaard
Søren Paaske Johnsen
Henrik Nielsen
Anne Høy Seemann Vestergaard
Thomas Lyngaa
Kristina Grønborg Laut
Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
BMJ Open
author_facet Mette Asbjoern Neergaard
Søren Paaske Johnsen
Henrik Nielsen
Anne Høy Seemann Vestergaard
Thomas Lyngaa
Kristina Grønborg Laut
author_sort Mette Asbjoern Neergaard
title Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
title_short Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
title_full Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
title_fullStr Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
title_full_unstemmed Hospitalisation at the end of life among cancer and non-cancer patients in Denmark: a nationwide register-based cohort study
title_sort hospitalisation at the end of life among cancer and non-cancer patients in denmark: a nationwide register-based cohort study
publisher BMJ Publishing Group
series BMJ Open
issn 2044-6055
publishDate 2020-06-01
description Objectives End-of-life hospitalisations may not be associated with improved quality of life. Studies indicate differences in end-of-life care for cancer and non-cancer patients; however, data on hospital utilisation are sparse. This study aimed to compare end-of-life hospitalisation and place of death among patients dying from cancer, heart failure or chronic obstructive pulmonary disease (COPD).Design A nationwide register-based cohort study.Setting Data on all in-hospital admissions obtained from nationwide Danish medical registries.Participants All decedents dying from cancer, heart failure or COPD disease in Denmark between 2006 and 2015.Outcome measures Data on all in-hospital admissions within 6 months and 30 days before death as well as place of death. Comparisons were made according to cause of death while adjusting for age, sex, comorbidity, partner status and residential region.Results Among 154 235 decedents, the median total bed days in hospital within 6 months before death was 19 days for cancer patients, 10 days for patients with heart failure and 11 days for patients with COPD. Within 30 days before death, this was 9 days for cancer patients, and 6 days for patients with heart failure and COPD. Compared with cancer patients, the adjusted relative bed day use was 0.65 (95% CI, 0.63 to 0.68) for heart failure patients and 0.68 (95% CI, 0.66 to 0.69) for patients with COPD within 6 months before death. Correspondingly, this was 0.65 (95% CI, 0.63 to 0.68) and 0.70 (95% CI, 0.68 to 0.71) within 30 days before death.Patients had almost the same risk of dying in hospital independently of death cause (46.2% to 56.0%).Conclusion Patients with cancer, heart failure and COPD all spent considerable part of their end of life in hospital. Hospital use was highest among cancer patients; however, absolute differences were small.
url https://bmjopen.bmj.com/content/10/6/e033493.full
work_keys_str_mv AT metteasbjoernneergaard hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
AT sørenpaaskejohnsen hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
AT henriknielsen hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
AT annehøyseemannvestergaard hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
AT thomaslyngaa hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
AT kristinagrønborglaut hospitalisationattheendoflifeamongcancerandnoncancerpatientsindenmarkanationwideregisterbasedcohortstudy
_version_ 1724221946399293440