STAT3 activation by catalpol promotes osteogenesis-angiogenesis coupling, thus accelerating osteoporotic bone repair

STAT3 activation by catalpol promotes osteogenesis-angiogenesis coupling, thus accelerating osteoporotic bone repair

Abstract Background Bone fracture repair has gained a lot of attention due to the high incidence of delayed union or even nonunion especially in osteoporotic patients, resulting in a dreadful impact on the quality of life. However, current therapies involve the costly expense and hence become unaffo...

Full description

Bibliographic Details
Main Authors: Liang Chen, Ri-Yan Zhang, Jun Xie, Jia-Yi Yang, Kang-Hao Fang, Chen-Xuan Hong, Rong-Bo Yang, Najeeb Bsoul, Lei Yang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Catalpol
Bone marrow mesenchymal stem cells
JAK2/STAT3 signaling
Osteoporosis
Bone repair
Online Access:https://doi.org/10.1186/s13287-021-02178-z

Internet

https://doi.org/10.1186/s13287-021-02178-z

Similar Items