PTPN11 (SHP2) Is Indispensable for Growth Factors and Cytokine Signal Transduction During Bovine Oocyte Maturation and Blastocyst Development

PTPN11 (SHP2) Is Indispensable for Growth Factors and Cytokine Signal Transduction During Bovine Oocyte Maturation and Blastocyst Development

This study was aimed to investigate the role of SHP2 (Src-homology-2-containing phosphotyrosine phosphatase) in intricate signaling networks invoked by bovine oocyte to achieve maturation and blastocyst development. <i>PTPN11</i> (Protein Tyrosine Phosphatase, non-receptor type 11) encod...

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Bibliographic Details
Main Authors: Muhammad Idrees, Lianguang Xu, Seok-Hwan Song, Myeong-Don Joo, Kyeong-Lim Lee, Tahir Muhammad, Marwa El Sheikh, Tabinda Sidrat, Il-Keun Kong
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
shp2 (<i>ptpn11</i>)
phps1
cisplatin
growth factors
cytokines
map kinases
pi3k/akt
blastocyst
Online Access:https://www.mdpi.com/2073-4409/8/10/1272

Internet

https://www.mdpi.com/2073-4409/8/10/1272

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