Multiplatform Investigation of Plasma and Tissue Lipid Signatures of Breast Cancer Using Mass Spectrometry Tools

Multiplatform Investigation of Plasma and Tissue Lipid Signatures of Breast Cancer Using Mass Spectrometry Tools

Plasma and tissue from breast cancer patients are valuable for diagnostic/prognostic purposes and are accessible by multiple mass spectrometry (MS) tools. Liquid chromatography-mass spectrometry (LC-MS) and ambient mass spectrometry imaging (MSI) were shown to be robust and reproducible technologies...

Full description

Bibliographic Details
Main Authors:	Alex Ap. Rosini Silva, Marcella R. Cardoso, Luciana Montes Resende, John Q. Lin, Fernando Guimaraes, Geisilene R. Paiva Silva, Michael Murgu, Denise Gonçalves Priolli, Marcos N. Eberlin, Alessandra Tata, Livia S. Eberlin, Sophie F. M. Derchain, Andreia M. Porcari
Format:	Article
Language:	English
Published:	MDPI AG 2020-05-01
Series:	International Journal of Molecular Sciences
Subjects:	breast cancer liquid chromatography-mass spectrometry desorption-electrospray-ionization—mass spectrometry imaging lipidomics plasma tumor tissue
Online Access:	https://www.mdpi.com/1422-0067/21/10/3611

Similar Items

Accurate Quantification of Lipid Species by Electrospray Ionization Mass Spectrometry — Meets a Key Challenge in Lipidomics
by: Kui Yang, et al.
Published: (2011-11-01)

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species
by: Stephen B. Milne, et al.
Published: (2005-08-01)

Shotgun lipidomics of phosphoethanolamine-containing lipids in biological samples after one-step in situ derivatization
by: Xianlin Han, et al.
Published: (2005-07-01)

DMS as an orthogonal separation to LC/ESI/MS/MS for quantifying isomeric cerebrosides in plasma and cerebrospinal fluid[S]
by: Hongbin Xu, et al.
Published: (2019-01-01)

Biopolymer analysis by electrospray ionization and tandem mass spectrometry
by: Keller, Karin Mia
Published: (2008)

Development of atmospheric pressure ionization techniques for mass spectrometry of biomolecules.
Published: (2013)

Desorption Electrospray Ionization Mass Spectrometry Imaging: Instrumentation, Optimization and Capabilities
by: Dhunna, Manan
Published: (2014)

Characterization of phthiocerol and phthiodiolone dimycocerosate esters of M. tuberculosis by multiple-stage linear ion-trap MS
by: Kelly N. Flentie, et al.
Published: (2016-01-01)

Towards the Development of a Proteomics Workflow for High-throughput Protein Biomarker Discovery
by: Wall, Mark James
Published: (2010)

The Effect of Exercise on the Skeletal Muscle Phospholipidome of Rats Fed a High-Fat Diet
by: Jong Sam Lee, et al.
Published: (2010-10-01)

Applications and fundamental characterization of open air and acoustic-driven ionization methods
by: Hampton, Christina Young
Published: (2009)

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples
by: Xianlin Han, et al.
Published: (2006-04-01)

A novel tip design for electrospray mass spectrometry at nanoliter flowrate.
Published: (2001)

Targeted analysis of ganglioside and sulfatide molecular species by LC/ESI-MS/MS with theoretically expanded multiple reaction monitorings⃞
by: Kazutaka Ikeda, et al.
Published: (2008-12-01)

Eletroforese capilar acoplada à espectrometria de massas (CE-MS): vinte anos de desenvolvimento Capillary electrophoresis coupled to mass spectrometry (CE-MS): twenty years of development
by: Nilson Antonio Assunção, et al.
Published: (2008-01-01)

Microfluidic Interfaces for Mass Spectrometry: Methods and Applications
by: Yang, Hao
Published: (2011)

Microfluidic Interfaces for Mass Spectrometry: Methods and Applications
by: Yang, Hao
Published: (2011)

Development and Applications of Liquid Sample Desorption Electrospray Ionization Mass Spectrometry (DESI-MS)
by: Miao, Zhixin
Published: (2012)

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction1[S]
by: Christian Marsching, et al.
Published: (2014-11-01)

Seminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient mice
by: Keiko Tadano-Aritomi, et al.
Published: (2003-09-01)

Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS)
by: G. Liebisch, et al.
Published: (1999-08-01)

Espectrometria de massas com ionização por "electrospray": processos químicos envolvidos na formação de íons de substâncias orgânicas de baixo peso molecular
by: Crotti Antônio Eduardo Miller, et al.
Published: (2006-01-01)

Mass spectrometric analysis of the reactivity of trityl cation
by: Wei, Alan An Jung
Published: (2019)

Study on the ion formation process(es) in matrix-assisted laser desorption/ionization mass spectrometry.
Published: (1997)

Quantification of Signaling Lipids by Nano-Electrospray Ionization Tandem Mass Spectrometry (Nano-ESI MS/MS)
by: Mathias Haag, et al.
Published: (2012-01-01)

A comprehensive insight into the lipid composition of Myxococcus xanthus by UPLC-ESI-MS[S]
by: Wolfram Lorenzen, et al.
Published: (2014-12-01)

Copper complexes formed by 3,5-bis(2,2′-bipyridin-4-ylethynyl)benzoic acid and its methyl and ethyl esters as studied by electrospray ionization mass spectrometry
by: Frański Rafał, et al.
Published: (2013-12-01)

Electrospray mass spectrometry of human hair wax esters
by: Fitzgerald Mark, et al.
Published: (2007-05-01)

Estudo por espectrometria de massas de soluções de hidróxi(tosilóxi)iodobenzeno: propostas para mecanismos de desproporção
by: Ramon S. Vasconcelos, et al.
Published: (2012-01-01)

Development of Ambient Mass Spectrometry for Protein/Peptide Characterization, Solvent-Free Analysis, and Electrochemical Reaction Monitoring
by: Liu, Pengyuan
Published: (2015)

Liquid chromatography coupled with electrospray-ionization mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry method development and applications for the analysis of food and medicinal herbs
by: Lee, Kim Chung
Published: (2009)

Characterization of Nucleosides and Nucleobases in Natural Cordyceps by HILIC–ESI/TOF/MS and HILIC–ESI/MS
by: Bin Yang, et al.
Published: (2013-08-01)

Identification of phosphatidylserylglutamate: a novel minor lipid in Escherichia coli
by: Teresa A. Garrett, et al.
Published: (2009-08-01)

Fundamentals of ambient metastable-induced chemical ionization mass spectrometry and atmospheric pressure ion mobility spectrometry
by: Harris, Glenn A.
Published: (2011)

ESI-MS spectra of 3-cyano-4-(substituted phenyl)-6-phenyl-2(1H)-pyridinones
by: BRATISLAV Ž. JOVANOVIĆ, et al.
Published: (2009-03-01)

A microfabricated rapid desalting device for integration with electrospraying tip
by: Tibavinsky, Ivan Andres
Published: (2014)

Quantification of seminolipid by LC-ESI-MS/MS-multiple reaction monitoring: compensatory levels in Cgt mice[S]
by: Kessiri Kongmanas, et al.
Published: (2010-12-01)

Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells
by: Anthony D. Postle, et al.
Published: (2006-06-01)

Chromium interaction with O-donor humic-like ligands using electrospray-ionization mass spectrometry
by: Anđelković Darko H., et al.
Published: (2013-01-01)

Applications of Nanomanipulation Coupled to Nanospray Mass Spectrometry in Trace Fiber Analysis and Cellular Lipid Analysis.
by: Ledbetter, Nicole
Published: (2008)