Vaginal Microbiota and Cytokine Microenvironment in HPV Clearance/Persistence in Women Surgically Treated for Cervical Intraepithelial Neoplasia: An Observational Prospective Study

Vaginal Microbiota and Cytokine Microenvironment in HPV Clearance/Persistence in Women Surgically Treated for Cervical Intraepithelial Neoplasia: An Observational Prospective Study

High-risk human papillomaviruses (hrHPVs) are causally related to cervical intraepithelial neoplasia (CIN) and subsequent cervical cancer (CC). The vaginal microbiome has been suggested to play a role in the development of CC, but the effect of conservative surgical treatment on the microbiome and h...

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Bibliographic Details
Main Authors: Elisabetta Caselli, Maria D’Accolti, Erica Santi, Irene Soffritti, Sara Conzadori, Sante Mazzacane, Pantaleo Greco, Carlo Contini, Gloria Bonaccorsi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
human papillomavirus
cervical neoplasia
surgical intervention
vaginal microbiome
vaginal cytokine
HPV clearance
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.540900/full

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