Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies

Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies

<p>Abstract</p> <p>Background</p> <p>Activated mast cells are present within airway smooth muscle (ASM) bundles in eosinophilic asthma. ASM production of the chemokine CXCL10 plays a role in their recruitment. Thus the effects of glucocorticoids (fluticasone, budesonide...

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Bibliographic Details
Main Authors: Seidel Petra, Alkhouri Hatem, Lalor Daniel J, Burgess Janette K, Armour Carol L, Hughes J
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Respiratory Research
Subjects:
Mast cell chemoattractant
Glucocorticoids
Long-acting β2-agonists
Salmeterol
Fluticasone
Ciglitazone
Rosiglitazone
Online Access:http://respiratory-research.com/content/13/1/90

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