Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication

Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication

Risperidone is a safe second-generation antipsychotic which is rarely associated with the emergence of a few adverse effects, such as oral lesions and stomatitis. We report the case of a 77-year-old woman affected by a neurocognitive disorder with psychotic features and treated with risperidone 2 mg...

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Main Authors: Andrea Amerio, Andrea Aguglia, Luca Proietti, Alessandra Costanza, Gianluca Serafini, Mario Amore
Format: Article
Language:English
Published: BMJ Publishing Group 2020-09-01
Series:General Psychiatry
Online Access:https://gpsych.bmj.com/content/33/5/e100228.full
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spelling doaj-8d90172d83274a52986165b27c56e3812020-11-25T02:42:03ZengBMJ Publishing GroupGeneral Psychiatry2517-729X2020-09-0133510.1136/gpsych-2020-100228Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medicationAndrea Amerio0Andrea Aguglia1Luca Proietti2Alessandra Costanza3Gianluca Serafini4Mario Amore51 Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Section of Psychiatry, University of Genoa, Genoa, Italy 1 Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Section of Psychiatry, University of Genoa, Genoa, Italy 1 Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Section of Psychiatry, University of Genoa, Genoa, Italy 4 Department of Psychiatry, Faculty of Medicine, University of Geneva (UNIGE), Geneva, Switzerland 1 Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Section of Psychiatry, University of Genoa, Genoa, Italy 1 Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), Section of Psychiatry, University of Genoa, Genoa, Italy Risperidone is a safe second-generation antipsychotic which is rarely associated with the emergence of a few adverse effects, such as oral lesions and stomatitis. We report the case of a 77-year-old woman affected by a neurocognitive disorder with psychotic features and treated with risperidone 2 mg/day. After 1 week, she showed a burning mouth syndrome with oral lesions and risperidone was discontinued. Antipsychotic-induced oral ulcerations may be caused by the reduction of saliva protection with minor adverse effects related to oral movement disorders or impairment of the bacterial flora of saliva.https://gpsych.bmj.com/content/33/5/e100228.full
collection DOAJ
language English
format Article
sources DOAJ
author Andrea Amerio
Andrea Aguglia
Luca Proietti
Alessandra Costanza
Gianluca Serafini
Mario Amore
spellingShingle Andrea Amerio
Andrea Aguglia
Luca Proietti
Alessandra Costanza
Gianluca Serafini
Mario Amore
Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
General Psychiatry
author_facet Andrea Amerio
Andrea Aguglia
Luca Proietti
Alessandra Costanza
Gianluca Serafini
Mario Amore
author_sort Andrea Amerio
title Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
title_short Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
title_full Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
title_fullStr Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
title_full_unstemmed Oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
title_sort oral mucositis induced by risperidone: rare side effect of a frequently prescribed medication
publisher BMJ Publishing Group
series General Psychiatry
issn 2517-729X
publishDate 2020-09-01
description Risperidone is a safe second-generation antipsychotic which is rarely associated with the emergence of a few adverse effects, such as oral lesions and stomatitis. We report the case of a 77-year-old woman affected by a neurocognitive disorder with psychotic features and treated with risperidone 2 mg/day. After 1 week, she showed a burning mouth syndrome with oral lesions and risperidone was discontinued. Antipsychotic-induced oral ulcerations may be caused by the reduction of saliva protection with minor adverse effects related to oral movement disorders or impairment of the bacterial flora of saliva.
url https://gpsych.bmj.com/content/33/5/e100228.full
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