From Serotonin to Neuroplasticity: Evolvement of Theories for Major Depressive Disorder

The serotonin (5-HT) hypothesis of depression has played an important role in the history of psychiatry, yet it has also been criticized for the delayed onset and inadequate efficacy of selective serotonin reuptake inhibitors (SSRIs). With evolvement of neuroscience, the neuroplasticity hypothesis o...

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Bibliographic Details
Main Authors: Bangshan Liu, Jin Liu, Mi Wang, Yan Zhang, Lingjiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00305/full