Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo

Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo

Malignant glioma is a severe cancer with a poor prognosis. Local occurrence and rare metastases of malignant glioma make it a suitable target for gene therapy. Several studies have demonstrated the importance of Src kinase in different cancers. However, these studies have focused mainly on Src-defic...

Full description

Bibliographic Details
Main Authors: Hanna Stedt, Laura Alasaarela, Haritha Samaranayake, Jere Pikkarainen, Ann-Marie Määttä, Ivana Kholová, Aaron S. Parker, Seppo Ylä-Herttuala
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
glioma
lentivirus
MRI
RNA interference
Src
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300786

Similar Items

Similar Items