A Bioinspired in vitro Lung Model to Study Particokinetics of Nano-/Microparticles Under Cyclic Stretch and Air-Liquid Interface Conditions

A Bioinspired in vitro Lung Model to Study Particokinetics of Nano-/Microparticles Under Cyclic Stretch and Air-Liquid Interface Conditions

Evolution has endowed the lung with exceptional design providing a large surface area for gas exchange area (ca. 100 m2) in a relatively small tissue volume (ca. 6 L). This is possible due to a complex tissue architecture that has resulted in one of the most challenging organs to be recreated in the...

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Bibliographic Details
Main Authors: Ali Doryab, Mehmet Berat Taskin, Philipp Stahlhut, Andreas Schröppel, Sezer Orak, Carola Voss, Arti Ahluwalia, Markus Rehberg, Anne Hilgendorff, Tobias Stöger, Jürgen Groll, Otmar Schmid
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
lung cell model
cyclic stretch
ALI culture
bioinspired membrane
particle study
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.616830/full

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