Pancreatic GLP-1r binding potential is reduced in insulin-resistant pigs
Introduction The insulinotropic capacity of exogenous glucagon like peptide-1 (GLP-1) is reduced in type 2 diabetes and the insulin-resistant obese. We have tested the hypothesis that this response is the consequence of a reduced pancreatic GLP-1 receptor (GLP-1r) density in insulin-resistant obese...
Main Authors: | Charles-Henri Malbert, Alain Chauvin, Michael Horowitz, Karen L Jones |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-12-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/8/2/e001540.full |
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