Pilus operon evolution in Streptococcus pneumoniae is driven by positive selection and recombination.
BACKGROUND: The evolution of bacterial organelles involved in host-pathogen interactions is subject to intense and competing selective pressures due to the need to maintain function while escaping the host immune response. To characterize the interplay of these forces in an important pathogen, we se...
Main Authors: | Alessandro Muzzi, Monica Moschioni, Antonello Covacci, Rino Rappuoli, Claudio Donati |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2576445?pdf=render |
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