Developing pulmonary vasculopathy in systemic sclerosis, detected with non-invasive cardiopulmonary exercise testing.

BACKGROUND: Patients with systemic sclerosis (SSc) may develop exercise intolerance due to musculoskeletal involvement, restrictive lung disease, left ventricular dysfunction, or pulmonary vasculopathy (PV). The latter is particularly important since it may lead to lethal pulmonary arterial hyperten...

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Bibliographic Details
Main Authors: Daniel Dumitrescu, Ronald J Oudiz, George Karpouzas, Arsen Hovanesyan, Amali Jayasinghe, James E Hansen, Stephan Rosenkranz, Karlman Wasserman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001444?pdf=render