The Anticancer Effect of (1S,2S,3E,7E,11E)-3,7,11, 15-Cembratetraen-17,2-olide(LS-1) through the Activation of TGF-β Signaling in SNU-C5/5-FU, Fluorouracil-Resistant Human Colon Cancer Cells

The Anticancer Effect of (1S,2S,3E,7E,11E)-3,7,11, 15-Cembratetraen-17,2-olide(LS-1) through the Activation of TGF-β Signaling in SNU-C5/5-FU, Fluorouracil-Resistant Human Colon Cancer Cells

The anticancer effect of (1S,2S,3E,7E,11E)-3,7,11,15-cembratetraen-17,2-olide (LS-1) from Lobophytum sp. has been already reported in HT-29 human colorectal cancer cells. In this study, we examined the effect of LS-1 on the apoptosis induction of SNU-C5/5-FU, fluorouracil-resistant human colon canc...

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Bibliographic Details
Main Authors: Eun-Ji Kim, Jung-Il Kang, Jeon-Won Kwak, Chan-Hee Jeon, Nguyen-Huu Tung, Young-Ho Kim, Cheol-Hee Choi, Jin-Won Hyun, Young-Sang Koh, Eun-Sook Yoo, Hee-Kyoung Kang
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Marine Drugs
Subjects:
LS-1
SNU-C5/5-FU
apoptosis
TGF-β signaling
carcinoembryonic antigen
Online Access:http://www.mdpi.com/1660-3397/13/3/1340

Internet

http://www.mdpi.com/1660-3397/13/3/1340

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