Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing.

Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing.

Intratumoral genetic heterogeneity may impact disease outcome. Gold standard for dissecting clonal heterogeneity are single-cell analyses. Here, we present an efficient workflow based on an advanced Single-Cell Printer (SCP) device for the study of gene variants in single cancer cells. To allow for...

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Bibliographic Details
Main Authors: Julian Riba, Nathalie Renz, Christoph Niemöller, Sabine Bleul, Dietmar Pfeifer, Juliane M Stosch, Klaus H Metzeler, Björn Hackanson, Michael Lübbert, Justus Duyster, Peter Koltay, Roland Zengerle, Rainer Claus, Stefan Zimmermann, Heiko Becker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033393?pdf=render

Internet

http://europepmc.org/articles/PMC5033393?pdf=render

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