Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA

Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA

Endonuclease IV (EndoIV) is a DNA damage-specific endonuclease that mainly hydrolyzes the phosphodiester bond located at 5′ of an apurinic/apyrimidinic (AP) site in DNA. EndoIV also possesses 3′-exonuclease activity for removing 3′-blocking groups and normal nucleotides...

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Bibliographic Details
Main Authors:	Wei-Wei Wang, Huan Zhou, Juan-Juan Xie, Gang-Shun Yi, Jian-Hua He, Feng-Ping Wang, Xiang Xiao, Xi-Peng Liu
Format:	Article
Language:	English
Published:	MDPI AG 2018-12-01
Series:	International Journal of Molecular Sciences
Subjects:	Thermococcus eurythermalis endonuclease IV AP site analogue spacer DNA repair
Online Access:	http://www.mdpi.com/1422-0067/20/1/69

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