Current Outlook on Autophagy in Human Leukemia: Foe in Cancer Stem Cells and Drug Resistance, Friend in New Therapeutic Interventions

Current Outlook on Autophagy in Human Leukemia: Foe in Cancer Stem Cells and Drug Resistance, Friend in New Therapeutic Interventions

Autophagy is an evolutionarily conserved cellular recycling process in cell homeostasis and stress adaptation. It confers protection and promotes survival in response to metabolic/environmental stress, and is upregulated in response to nutrient deprivation, hypoxia, and chemotherapies. Autophagy is...

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Bibliographic Details
Main Authors:	Katharina Rothe, Vanessa Porter, Xiaoyan Jiang
Format:	Article
Language:	English
Published:	MDPI AG 2019-01-01
Series:	International Journal of Molecular Sciences
Subjects:	autophagy hematological malignancies chronic myeloid leukemia acute myeloid leukemia cancer stem cells leukemia leukemic stem cells drug resistance autophagy inhibitors
Online Access:	https://www.mdpi.com/1422-0067/20/3/461

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