The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

Preventing premature interaction of pre-ribosomes with the translation apparatus is essential for translational accuracy. Hence, the final maturation step releasing functional 40S ribosomal subunits, namely processing of the 18S ribosomal RNA 3′ end, is safeguarded by the protein DIM2, which both in...

Full description

Bibliographic Details
Main Authors: Laura Plassart, Ramtin Shayan, Christian Montellese, Dana Rinaldi, Natacha Larburu, Carole Pichereaux, Carine Froment, Simon Lebaron, Marie-Françoise O'Donohue, Ulrike Kutay, Julien Marcoux, Pierre-Emmanuel Gleizes, Celia Plisson-Chastang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
human ribosome biogenesis
small ribosomal subunit
structure-function study
cryo-EM
pre-rRNA processing
Online Access:https://elifesciences.org/articles/61254

Internet

https://elifesciences.org/articles/61254

Similar Items