Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell

Antiviral Immunotoxin Against Bovine herpesvirus-1: Targeted Inhibition of Viral Replication and Apoptosis of Infected Cell

Bovine herpesvirus 1 (BoHV-1) is a highly contagious viral pathogen which causes infectious bovine rhinotracheitis in cattle worldwide. Currently, there is no antiviral prophylactic treatment available capable of mitigating the disease impact and facilitating recovery from latent infection. In this...

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Bibliographic Details
Main Authors: Jian Xu, Xiaoyang Li, Bo Jiang, Xiaoyu Feng, Jing Wu, Yunhong Cai, Xixi Zhang, Xiufen Huang, Joshua E. Sealy, Munir Iqbal, Yongqing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
Bovine herpesvirus-1
immunotoxin
antiviral function
specific binding
targeted cytotoxic effect
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00653/full

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