A New Method for Chromosomes Preparation by ATP-Competitive Inhibitor SP600125 via Enhancement of Endomitosis in Fish

A New Method for Chromosomes Preparation by ATP-Competitive Inhibitor SP600125 via Enhancement of Endomitosis in Fish

Previous studies have suggested that 1,9-Pyrazoloanthrone, known as SP600125, can induce cell polyploidization. However, what is the phase of cell cycle arrest caused by SP600125 and the underlying regulation is still an interesting issue to be further addressed. Research in this article shows that...

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Bibliographic Details
Main Authors: Wenting Xu, Yanxiu Mo, Yu He, Yunpeng Fan, Guomin He, Wen Fu, Shujuan Chen, Jinhui Liu, Wenbin Liu, Liangyue Peng, Yamei Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
SP600125
endomitosis
p53
spindle assembly checkpoint
chromosome
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.606496/full

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