Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults
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2020-09-01
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doaj-8d39c5bedf1b411e9d94566602ddf84b2021-07-21T16:14:59ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-041437Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adultsFlorence Ader0François-Xavier Lescure1Laetitia Moinot2Christelle Delmas3Hélène Espérou4Laurent Abel5Benjamin Leveau6Vinca Icard7Toni Alfaiate8Charles Burdet9France Mentré10Marion SchneiderNathan Peiffer-SmadjaJulien PoissyLila BouadmaBruno Lina11Florence Morfin-SherpaMaude BouscambertAlexandre GaymardGilles Peytavin12Jeremie Guedj13Cedric Laouenan14Drifa BelhadiAxelle DupontBasma BasliAnissa ChairSamira LaribiJulie LevelMarie-Capucine TellierAline DechanetDominique CostagliolaSandrine Couffin-CadierguesJuliette SaillardClaire FougerouCarole CagnotSoizic Le MestreDelphine Lebrasseur-LonguetVentzislava Petrov-SanchezAlpha DialloNoéMie MercierSarah TubianaBenjamin HamzeAmbre GelleyMarion NoretEric D’OrtenzioOriane PuechalCaroline Semaille151 Service de Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Lyon, France professorBordeaux Population Health Research Center, INSERM, Bordeaux, France12 Institut de santé publique, Pôle recherche clinique, Institut national de la santé et de la recherche médicale, Paris, France12 Institut de santé publique, Pôle recherche clinique, Institut national de la santé et de la recherche médicale, Paris, FranceLaboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, U980 Necker Medical School, Paris, FranceCentre de ressources biologiques Nord, Hospices Civils de Lyon, Lyon, FranceCentre de ressources biologiques Nord, Hospices Civils de Lyon, Lyon, France5APHP, Department of Epidemiology and Clinical Research, Hôpital Bichat, Paris, France1 IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, INSERM, Paris, France 1 IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, INSERM, Paris, France 9 Faculté de Médecine Lyon Est, VirPatH, EA 4610, Université Claude Bernard Lyon 1, Lyon, France Claude Bernard Bichat Hospital, Toxicology, 46 Rue Henri Huchard, Paris, 75018, France2Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, Los Alamos, New Mexico, USA2University Paris Diderot, Sorbonne Paris Cité, Paris, FranceDépartement des maladies infectieuses, Institut de Veille Sanitaire, Saint-Maurice, Francehttps://bmjopen.bmj.com/content/10/9/e041437.full |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Florence Ader François-Xavier Lescure Laetitia Moinot Christelle Delmas Hélène Espérou Laurent Abel Benjamin Leveau Vinca Icard Toni Alfaiate Charles Burdet France Mentré Marion Schneider Nathan Peiffer-Smadja Julien Poissy Lila Bouadma Bruno Lina Florence Morfin-Sherpa Maude Bouscambert Alexandre Gaymard Gilles Peytavin Jeremie Guedj Cedric Laouenan Drifa Belhadi Axelle Dupont Basma Basli Anissa Chair Samira Laribi Julie Level Marie-Capucine Tellier Aline Dechanet Dominique Costagliola Sandrine Couffin-Cadiergues Juliette Saillard Claire Fougerou Carole Cagnot Soizic Le Mestre Delphine Lebrasseur-Longuet Ventzislava Petrov-Sanchez Alpha Diallo NoéMie Mercier Sarah Tubiana Benjamin Hamze Ambre Gelley Marion Noret Eric D’Ortenzio Oriane Puechal Caroline Semaille |
spellingShingle |
Florence Ader François-Xavier Lescure Laetitia Moinot Christelle Delmas Hélène Espérou Laurent Abel Benjamin Leveau Vinca Icard Toni Alfaiate Charles Burdet France Mentré Marion Schneider Nathan Peiffer-Smadja Julien Poissy Lila Bouadma Bruno Lina Florence Morfin-Sherpa Maude Bouscambert Alexandre Gaymard Gilles Peytavin Jeremie Guedj Cedric Laouenan Drifa Belhadi Axelle Dupont Basma Basli Anissa Chair Samira Laribi Julie Level Marie-Capucine Tellier Aline Dechanet Dominique Costagliola Sandrine Couffin-Cadiergues Juliette Saillard Claire Fougerou Carole Cagnot Soizic Le Mestre Delphine Lebrasseur-Longuet Ventzislava Petrov-Sanchez Alpha Diallo NoéMie Mercier Sarah Tubiana Benjamin Hamze Ambre Gelley Marion Noret Eric D’Ortenzio Oriane Puechal Caroline Semaille Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults BMJ Open |
author_facet |
Florence Ader François-Xavier Lescure Laetitia Moinot Christelle Delmas Hélène Espérou Laurent Abel Benjamin Leveau Vinca Icard Toni Alfaiate Charles Burdet France Mentré Marion Schneider Nathan Peiffer-Smadja Julien Poissy Lila Bouadma Bruno Lina Florence Morfin-Sherpa Maude Bouscambert Alexandre Gaymard Gilles Peytavin Jeremie Guedj Cedric Laouenan Drifa Belhadi Axelle Dupont Basma Basli Anissa Chair Samira Laribi Julie Level Marie-Capucine Tellier Aline Dechanet Dominique Costagliola Sandrine Couffin-Cadiergues Juliette Saillard Claire Fougerou Carole Cagnot Soizic Le Mestre Delphine Lebrasseur-Longuet Ventzislava Petrov-Sanchez Alpha Diallo NoéMie Mercier Sarah Tubiana Benjamin Hamze Ambre Gelley Marion Noret Eric D’Ortenzio Oriane Puechal Caroline Semaille |
author_sort |
Florence Ader |
title |
Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults |
title_short |
Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults |
title_full |
Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults |
title_fullStr |
Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults |
title_full_unstemmed |
Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults |
title_sort |
protocol for the discovery trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for covid-19 in hospitalised adults |
publisher |
BMJ Publishing Group |
series |
BMJ Open |
issn |
2044-6055 |
publishDate |
2020-09-01 |
url |
https://bmjopen.bmj.com/content/10/9/e041437.full |
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