Loss of flavin adenine dinucleotide (FAD) impairs sperm function and male reproductive advantage in C. elegans

Loss of flavin adenine dinucleotide (FAD) impairs sperm function and male reproductive advantage in C. elegans

Exposure to environmental stress is clinically established to influence male reproductive health, but the impact of normal cellular metabolism on sperm quality is less well-defined. Here we show that impaired mitochondrial proline catabolism, reduces energy-storing flavin adenine dinucleotide (FAD)...

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Bibliographic Details
Main Authors: Chia-An Yen, Dana L Ruter, Christian D Turner, Shanshan Pang, Sean P Curran
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
spermatogenesis
mitochondria
reproduction
FAD
riboflavin
alh-6/ALDH4A1
Online Access:https://elifesciences.org/articles/52899

Internet

https://elifesciences.org/articles/52899

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