SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer.

SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer.

Tumor-associated macrophages (TAMs) play a role in tumor angiogenesis and are recruited into the tumor microenvironment (TME) by secreted chemokines, including Monocyte Chemoattractant Protein-1 (MCP-1/CCL2). Angiogenesis is required to sustain proliferation and enable metastasis of breast cancer (B...

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Bibliographic Details
Main Authors:	Elizabeth M Hultgren, Mitch E Patrick, Rick L Evans, Catherine T Stoos, Kristi A Egland
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5419604?pdf=render

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