THYROID HORMONE TREATED ASTROCYTES INDUCE MATURATION OF CEREBRAL CORTICAL NEURONS THROUGH MODULATION OF PROTEOGLYCAN LEVELS

THYROID HORMONE TREATED ASTROCYTES INDUCE MATURATION OF CEREBRAL CORTICAL NEURONS THROUGH MODULATION OF PROTEOGLYCAN LEVELS

Proper brain neuronal circuitry formation and synapse development is dependent on specific cues, either genetic or epigenetic, provided by the surrounding neural environment. Within these signals, thyroid hormones (T3 and T4) play crucial role in several steps of brain morphogenesis including prolif...

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Bibliographic Details
Main Authors: Romulo Sperduto Dezonne, Joice eStipursky, Ana Paula Bergamo Araujo, Jader eNones, Mauro Sérgio Gonçalves Pavão, Marimelia ePorcionatto, Flavia Carvalho Alcantara Gomes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Thyroid Hormones
astrocyte
Neurite outgrowth
extracellular matrix.
brain morphogenesis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00125/full

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