Inhibition of Nonsmall Cell Lung Cancer Cell Migration by Protein Arginine Methyltransferase 1-small Hairpin RNA Through Inhibiting Epithelial-mesenchymal Transition, Extracellular Matrix Degradation, and Src Phosphorylation In Vitro

Inhibition of Nonsmall Cell Lung Cancer Cell Migration by Protein Arginine Methyltransferase 1-small Hairpin RNA Through Inhibiting Epithelial-mesenchymal Transition, Extracellular Matrix Degradation, and Src Phosphorylation In Vitro

Background: Protein arginine methyltransferases 1 (PRMT1) is over-expressed in a variety of cancers, including lung cancer, and is correlated with a poor prognosis of tumor development. This study aimed to investigate the role of PRMT1 in nonsmall cell lung cancer (NSCLC) migration in vitro. Method...

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Bibliographic Details
Main Authors: Ting Zhang, Ge Cui, Yun-Liang Yao, Yue Guo, Qi-Chun Wang, Xi-Ning Li, Wen-Ming Feng
Format: Article
Language:English
Published: Wolters Kluwer 2015-01-01
Series:Chinese Medical Journal
Subjects:
Epithelial-mesenchymal Transition; Extracellular Matrix Degradation; Migration; Nonsmall Cell Lung Cancer; Protein Arginine Methyltransferases 1; Src
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=9;spage=1202;epage=1208;aulast=Zhang

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