Isolation and biological evaluation of some organogermanium(IV) complexes of sulfonamide imine

• Main Authors: Singh Nirmala, Kapoor Puja, Fahmi Nighat, Singh Ranvir
• Format: Article
• Language: English
• Published: De Gruyter 2011-09-01
• Series: Main Group Metal Chemistry
• Subjects: germanium; ligand; microwave energy; organogermanium complexes
• Online Access: https://doi.org/10.1515/mgmc.2011.004

Microwave-assisted synthesis and spectroscopic studies of trimethyl and triphenyl germanium(IV) chelates derived from the reactions of organogermanium chlorides with the sodium salt of a biologically active nitrogen donor ligand are described. The resulting products have been isolated and characterized by elemental analyses, molecular weight determinations and conductance measurements, Systronics-Vadodara, India. On the basis of electronic, infrared, 1H and 13C NMR spectral studies, trigonal bipyramidal geometry has been suggested for the resulting complexes. The biologically active ligand and its corresponding complexes have been examined with regard to antifungal and antibacterial activity against pathogenic fungi and bacteria, and the results are rather encouraging. Both the compounds have also been found to act as nematicides by reducing the number of nematodes (Meloidogyne incognita).