Positron emission tomography as a method for measuring drug delivery to tumors in vivo: the example of [11C]docetaxel

Systemic anticancer treatments fail in a substantial number of patients. This may be caused by inadequate uptake and penetration of drugs in malignant tumors. Consequently, improvement of drug delivery to solid tumors may enhance its efficacy. Before evaluating strategies to enhance drug uptake in t...

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Bibliographic Details
Main Authors: Astrid eVan Der Veldt, Egbert eSmit, Adriaan Anthonius Lammertsma
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00208/full