Dynamic chromatin organization during foregut development mediated by the organ selector gene PHA-4/FoxA.

Dynamic chromatin organization during foregut development mediated by the organ selector gene PHA-4/FoxA.

Central regulators of cell fate, or selector genes, establish the identity of cells by direct regulation of large cohorts of genes. In Caenorhabditis elegans, foregut (or pharynx) identity relies on the FoxA transcription factor PHA-4, which activates different sets of target genes at various times...

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Bibliographic Details
Main Authors: Tala H I Fakhouri, Jeff Stevenson, Andrew D Chisholm, Susan E Mango
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2920861?pdf=render

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