Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV

Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV

Interferons (IFNs) are considered the first line of defense against viral diseases. Due to their ability to modulate immune responses, they have become an attractive therapeutic option to control virus infections. In fact, like many other viruses, foot-and-mouth disease virus (FMDV), the most contag...

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Bibliographic Details
Main Authors: Fayna Diaz-San Segundo, Gisselle N. Medina, Paul Azzinaro, Joseph Gutkoska, Aishwarya Mogulothu, Sarah E. Attreed, Kimberly R. Lombardi, Jacob Shields, Teresa A. Hudock, Teresa de los Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Microbiology
Subjects:
FMDV
foot-and-mouth disease
type I interferon
IFN
PEGylation
biotherapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.668890/full

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