IL‐8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype

IL‐8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype

The adult mammalian liver exhibits a remarkable regenerative capacity, with different modes of regeneration according to the type and extent of injury. Hepatocyte–cholangiocyte biphenotypic liver progenitor cell populations appear under conditions of excessive injury. It has been reported that matur...

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Bibliographic Details
Main Authors: Tokio Sasaki, Yuji Suzuki, Keisuke Kakisaka, Ting Wang, Kazuyuki Ishida, Akiko Suzuki, Hiroaki Abe, Tamotsu Sugai, Yasuhiro Takikawa
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:FEBS Open Bio
Subjects:
cholangiocyte
interleukin‐8
mature hepatocyte
Sry HMG box protein 9
transdifferentiation
Online Access:https://doi.org/10.1002/2211-5463.12750

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