c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients

<p>Abstract</p> <p>Background</p> <p>To study whether and how c-MYC expression determines response to radio- and chemotherapy in childhood medulloblastoma (MB).</p> <p>Methods</p> <p>We used DAOY and UW228 human MB cells engineered to stably expr...

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Bibliographic Details
Main Authors: Stearns Duncan, Warmuth-Metz Monika, Gerber Nicolas U, Seifert Burkhardt, Pruschy Martin, von Hoff Katja, Shalaby Tarek, Oehler Christoph, von Bueren André O, Eberhart Charles G, Kortmann Rolf D, Rutkowski Stefan, Grotzer Michael A
Format: Article
Language:English
Published: BMC 2011-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/74