Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes

Preparation, characterization, pharmacokinetics and anticancer effects of PEGylated β-elemene liposomes

Objective: This study aimed to develop a new polyethylene glycol (PEG)ylated β-elemene liposome (PEG-Lipo-β-E) and evaluate its characterization, pharmacokinetics, antitumor effects and safety in vitro and in vivo. Methods: The liposomes were prepared by ethanol injection and high-pressure micro-jet...

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Bibliographic Details
Main Authors: Bingtao Zhai, Qibiao Wu, Wengang Wang, Mingming Zhang, Xuemeng Han, Qiujie Li, Peng Chen, Xiaying Chen, Xingxing Huang, Guohua Li, Qin Zhang, Ruonan Zhang, Yu Xiang, Shuiping Liu, Ting Duan, Jianshu Lou, Tian Xie, Xinbing Sui
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-02-01
Series:Cancer Biology & Medicine
Subjects:
β-elemene
pegylated liposome
pharmacokinetics
antitumor effect
bladder cancer
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1551

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