IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma

IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma

Indoleamine 2,3-dioxygenase (IDO1) plays an important role in tumor immune evasion. In this study, we investigated the changes of tumor IDO1 expression and CD8+ tumor-infiltrating lymphocytes (TILs) status in tumor microenvironment (TME) after neoadjuvant chemoradiotherapy (NCRT) or neoadjuvant chem...

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Bibliographic Details
Main Authors: Ruidi Jiao, Xiaoli Zheng, Yanan Sun, Zhuo Feng, Shuai Song, Hong Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
ESCC
IDO1
CD8
neoadjuvant therapy
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01099/full

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