How Can We Improve the Detection of Alpha1-Antitrypsin Deficiency?

The Z deficiency in α1-antitrypsin (A1ATD) is an under-recognized condition. Alpha1-antitrypsin (A1AT) is the main protein in the α1-globulin fraction of serum protein electrophoresis (SPE); however, evaluation of the α1-globulin protein fraction has received very little attention. Serum Z-type A1AT...

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Bibliographic Details
Main Authors: Ilaria Ferrarotti, Beata Poplawska-Wisniewska, Maria Teresa Trevisan, Janine Koepke, Marc Dresel, Rembert Koczulla, Stefania Ottaviani, Raffaele Baldo, Marina Gorrini, Giorgia Sala, Luana Cavallon, Tobias Welte, Joanna Chorostowska-Wynimko, Maurizio Luisetti, Sabina Janciauskiene
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4536179?pdf=render