New Brilliant Blue G Derivative as Pharmacological Tool in Retinal Surgery

New Brilliant Blue G Derivative as Pharmacological Tool in Retinal Surgery

Our study was aimed at assessing the retinal binding of a new synthetic Brilliant Blue G (BBG) derivative (pure benzyl-Brilliant Blue G; PBB) ophthalmic formulation, to improve vitreoretinal surgery procedure. Protein affinity of the new molecule was evaluated in vitro (cell-free assay) and in silic...

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Bibliographic Details
Main Authors: Angelo Spadaro, Marco Rao, Miriam Lorenti, Mario Rosario Romano, Antonio Augello, Chiara Maria Eandi, Chiara Bianca Maria Platania, Filippo Drago, Claudio Bucolo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
inner limiting membrane
retina
vitreoretinal surgery
Brilliant Blue G
pucker
drug design
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00708/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00708/full

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