Is Nonmicronized Diosmin 600 mg as Effective as Micronized Diosmin 900 mg plus Hesperidin 100 mg on Chronic Venous Disease Symptoms? Results of a Noninferiority Study

Is Nonmicronized Diosmin 600 mg as Effective as Micronized Diosmin 900 mg plus Hesperidin 100 mg on Chronic Venous Disease Symptoms? Results of a Noninferiority Study

Background. Phlebotonics have beneficial effects on some symptoms related to chronic venous disease (CVD) of the lower limbs. The most commonly used one is diosmin, available in a pure semisynthetic form or as a micronized purified flavonoid fraction. Patients and Methods. The primary objective of t...

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Bibliographic Details
Main Authors: Marcio Steinbruch, Carlos Nunes, Romualdo Gama, Renato Kaufman, Gustavo Gama, Mendel Suchmacher Neto, Rafael Nigri, Natasha Cytrynbaum, Lisa Brauer Oliveira, Isabelle Bertaina, François Verrière, Mauro Geller
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2020/4237204

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