Upregulation of PPARbeta/delta is associated with structural and functional changes in the type I diabetes rat diaphragm.

Upregulation of PPARbeta/delta is associated with structural and functional changes in the type I diabetes rat diaphragm.

Diabetes mellitus is associated with alterations in peripheral striated muscles and cardiomyopathy. We examined diaphragmatic function and fiber composition and identified the role of peroxisome proliferator-activated receptors (PPAR alpha and beta/delta) as a factor involved in diaphragm muscle pla...

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Bibliographic Details
Main Authors: Nadège Salvi, Aziz Guellich, Pierre Michelet, Alexandre Demoule, Morgan Le Guen, Laure Renou, Gisèle Bonne, Bruno Riou, Olivier Langeron, Catherine Coirault
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2900215?pdf=render

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