Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth

Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth

Stimulation of retinoic acid (RA) mediated signalling pathways following neural injury leads to regeneration in the adult nervous system and numerous studies have shown that the specific activation of the retinoic acid receptor β (RARβ) is required for this process. Here we identify a novel mechanis...

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Bibliographic Details
Main Authors: Maria B. Goncalves, Yue Wu, Diogo Trigo, Earl Clarke, Tony Malmqvist, John Grist, Carl Hobbs, Thomas P. Carlstedt, Jonathan P.T. Corcoran
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Neurobiology of Disease
Subjects:
Retinoic acid
Exosome
Axonal guidance
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302954

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