Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo.

There is a large body of scientific evidence suggesting that 3,3'-Diindolylmethane (DIM), a compound derived from the digestion of indole-3-carbinol, which is abundant in cruciferous vegetables, harbors anti-tumor activity in vitro and in vivo. Accumulating evidence suggests that AMP-activated...

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Bibliographic Details
Main Authors: Di Chen, Sanjeev Banerjee, Qiuzhi C Cui, Dejuan Kong, Fazlul H Sarkar, Q Ping Dou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3467201?pdf=render