Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications

Bioorthogonal chemistry has recently emerged to be one of the most powerful tools in drug discovery and chemical biology. The exploration of it has successfully advanced the field of natural product research. In this Perspective, we survey current strategies for the installation of chemical handles...

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Bibliographic Details
Main Authors: Xuejun eZhu, Wenjun eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2015.00011/full