Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue

Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue

A novel approach for precise determination of the optical scattering and absorption properties of porcine tissue using an optimized integrating sphere setup was applied. Measurements on several sample types (skin, muscle, adipose tissue, bone, cartilage, brain) in the spectral range between 400 nm a...

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Main Authors: Florian Bergmann, Florian Foschum, Leonie Marzel, Alwin Kienle
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Photonics
Subjects:
optical properties
biological tissue
integrating sphere
Online Access:https://www.mdpi.com/2304-6732/8/9/365
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spelling doaj-8c86776ab27a4bfebcad2251c6216a0d2021-09-26T00:58:04ZengMDPI AGPhotonics2304-67322021-08-01836536510.3390/photonics8090365Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine TissueFlorian Bergmann0Florian Foschum1Leonie Marzel2Alwin Kienle3Quantitative Imaging and Sensors, Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm, Helmholtzstr. 12, D-89081 Ulm, GermanyQuantitative Imaging and Sensors, Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm, Helmholtzstr. 12, D-89081 Ulm, GermanyQuantitative Imaging and Sensors, Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm, Helmholtzstr. 12, D-89081 Ulm, GermanyQuantitative Imaging and Sensors, Institut für Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm, Helmholtzstr. 12, D-89081 Ulm, GermanyA novel approach for precise determination of the optical scattering and absorption properties of porcine tissue using an optimized integrating sphere setup was applied. Measurements on several sample types (skin, muscle, adipose tissue, bone, cartilage, brain) in the spectral range between 400 nm and 1400 nm were performed. Due to the heterogeneity of biological samples, measurements on different individual animals as well as on different sections for each sample type were carried out. For all samples, we used an index matching method to reduce surface roughness effects and to prevent dehydration. The derived absorption spectra were used to estimate the concentration of important tissue chromophores such as water, oxy- and deoxyhemoglobin, collagen and fat.https://www.mdpi.com/2304-6732/8/9/365optical propertiesbiological tissueintegrating sphere
collection DOAJ
language English
format Article
sources DOAJ
author Florian Bergmann
Florian Foschum
Leonie Marzel
Alwin Kienle
spellingShingle Florian Bergmann
Florian Foschum
Leonie Marzel
Alwin Kienle
Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
Photonics
optical properties
biological tissue
integrating sphere
author_facet Florian Bergmann
Florian Foschum
Leonie Marzel
Alwin Kienle
author_sort Florian Bergmann
title Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
title_short Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
title_full Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
title_fullStr Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
title_full_unstemmed Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue
title_sort ex vivo determination of broadband absorption and effective scattering coefficients of porcine tissue
publisher MDPI AG
series Photonics
issn 2304-6732
publishDate 2021-08-01
description A novel approach for precise determination of the optical scattering and absorption properties of porcine tissue using an optimized integrating sphere setup was applied. Measurements on several sample types (skin, muscle, adipose tissue, bone, cartilage, brain) in the spectral range between 400 nm and 1400 nm were performed. Due to the heterogeneity of biological samples, measurements on different individual animals as well as on different sections for each sample type were carried out. For all samples, we used an index matching method to reduce surface roughness effects and to prevent dehydration. The derived absorption spectra were used to estimate the concentration of important tissue chromophores such as water, oxy- and deoxyhemoglobin, collagen and fat.
topic optical properties
biological tissue
integrating sphere
url https://www.mdpi.com/2304-6732/8/9/365
work_keys_str_mv AT florianbergmann exvivodeterminationofbroadbandabsorptionandeffectivescatteringcoefficientsofporcinetissue
AT florianfoschum exvivodeterminationofbroadbandabsorptionandeffectivescatteringcoefficientsofporcinetissue
AT leoniemarzel exvivodeterminationofbroadbandabsorptionandeffectivescatteringcoefficientsofporcinetissue
AT alwinkienle exvivodeterminationofbroadbandabsorptionandeffectivescatteringcoefficientsofporcinetissue
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