Further support for aneuploidy tolerance in wild yeast and effects of dosage compensation on gene copy-number evolution

In our prior work by Hose et al., we performed a genome-sequencing survey and reported that aneuploidy was frequently observed in wild strains of S. cerevisiae. We also profiled transcriptome abundance in naturally aneuploid isolates compared to isogenic euploid controls and found that 10–30% of amp...

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Bibliographic Details
Main Authors: Audrey P Gasch, James Hose, Michael A Newton, Maria Sardi, Mun Yong, Zhishi Wang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/14409