Adipokines, diabetes and atherosclerosis: an inflammatory association

Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, includi...

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Main Authors:	Leandro Ceotto Freitas Lima, Valdir de Andrade Barga, Maria edo Socorro de França Silva, Josiane de Campos Cruz, Sérgio Henrique Sousa Santos, Matheus Morais de Oliveira Monteiro, Camille M Balarini
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-11-01
Series:	Frontiers in Physiology
Subjects:	Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full

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spelling	doaj-8c7f60a81750460490a461d8c2d855ca2020-11-24T23:02:08ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2015-11-01610.3389/fphys.2015.00304163920Adipokines, diabetes and atherosclerosis: an inflammatory associationLeandro Ceotto Freitas Lima0Valdir de Andrade Barga1Maria edo Socorro de França Silva2Josiane de Campos Cruz3Sérgio Henrique Sousa Santos4Sérgio Henrique Sousa Santos5Matheus Morais de Oliveira Monteiro6Camille M Balarini7Camille M Balarini8Federal University of Minas GeraisFederal University of ParaibaFederal University of ParaibaFederal University of ParaibaFederal University of Minas GeraisState University of Montes ClarosFederal University of ParaibaFederal University of ParaibaFederal University of ParaibaCardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models.http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/fullAdipokinesAdiponectinAtherosclerosisObesitydiabetesTNFα
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Leandro Ceotto Freitas Lima Valdir de Andrade Barga Maria edo Socorro de França Silva Josiane de Campos Cruz Sérgio Henrique Sousa Santos Sérgio Henrique Sousa Santos Matheus Morais de Oliveira Monteiro Camille M Balarini Camille M Balarini
spellingShingle	Leandro Ceotto Freitas Lima Valdir de Andrade Barga Maria edo Socorro de França Silva Josiane de Campos Cruz Sérgio Henrique Sousa Santos Sérgio Henrique Sousa Santos Matheus Morais de Oliveira Monteiro Camille M Balarini Camille M Balarini Adipokines, diabetes and atherosclerosis: an inflammatory association Frontiers in Physiology Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα
author_facet	Leandro Ceotto Freitas Lima Valdir de Andrade Barga Maria edo Socorro de França Silva Josiane de Campos Cruz Sérgio Henrique Sousa Santos Sérgio Henrique Sousa Santos Matheus Morais de Oliveira Monteiro Camille M Balarini Camille M Balarini
author_sort	Leandro Ceotto Freitas Lima
title	Adipokines, diabetes and atherosclerosis: an inflammatory association
title_short	Adipokines, diabetes and atherosclerosis: an inflammatory association
title_full	Adipokines, diabetes and atherosclerosis: an inflammatory association
title_fullStr	Adipokines, diabetes and atherosclerosis: an inflammatory association
title_full_unstemmed	Adipokines, diabetes and atherosclerosis: an inflammatory association
title_sort	adipokines, diabetes and atherosclerosis: an inflammatory association
publisher	Frontiers Media S.A.
series	Frontiers in Physiology
issn	1664-042X
publishDate	2015-11-01
description	Cardiovascular diseases can be considered the most important cause of death in diabetic population and diabetes can in turn increase the risk of cardiovascular events. Inflammation process is currently recognized as responsible for the development and maintenance of diverse chronic diseases, including diabetes and atherosclerosis. Considering that adipose tissue is an important source of adipokines, which may present anti and proinflammatory effects, the aim of this review is to explore the role of the main adipokines in the pathophysiology of diabetes and atherosclerosis, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models.
topic	Adipokines Adiponectin Atherosclerosis Obesity diabetes TNFα
url	http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00304/full
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Adipokines, diabetes and atherosclerosis: an inflammatory association

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