Removal of pectoral muscle based on topographic map and shape-shifting silhouette

• Main Authors: Bushra Mughal, Nazeer Muhammad, Muhammad Sharif, Amjad Rehman, Tanzila Saba
• Format: Article
• Language: English
• Published: BMC 2018-08-01
• Series: BMC Cancer
• Subjects: Mediolateral-oblique (MLO); Pectoral muscle; Breast profile; Cranial-caudal (cc); Label and artifacts
• Online Access: http://link.springer.com/article/10.1186/s12885-018-4638-5

Abstract Background In digital mammography, finding accurate breast profile segmentation of women’s mammogram is considered a challenging task. The existence of the pectoral muscle may mislead the diagnosis of cancer due to its high-level similarity to breast body. In addition, some other challenges due to manifestation of the breast body pectoral muscle in the mammogram data include inaccurate estimation of the density level and assessment of the cancer cell. The discrete differentiation operator has been proven to eliminate the pectoral muscle before the analysis processing. Methods We propose a novel approach to remove the pectoral muscle in terms of the mediolateral-oblique observation of a mammogram using a discrete differentiation operator. This is used to detect the edges boundaries and to approximate the gradient value of the intensity function. Further refinement is achieved using a convex hull technique. This method is implemented on dataset provided by MIAS and 20 contrast enhanced digital mammographic images. Results To assess the performance of the proposed method, visual inspections by radiologist as well as calculation based on well-known metrics are observed. For calculation of performance metrics, the given pixels in pectoral muscle region of the input scans are calculated as ground truth. Conclusions Our approach tolerates an extensive variety of the pectoral muscle geometries with minimum risk of bias in breast profile than existing techniques.