A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease

Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of ta...

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Main Authors:	Yanhong Ma, Fanghao Cai, Yangyang Li, Jianghua Chen, Fei Han, Weiqiang Lin
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2020-09-01
Series:	Bioactive Materials
Subjects:	Chronic kidney disease Nanoparticles Diagnosis Treatment
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X20300840

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spelling	doaj-8c77eb96c1094da68ab9d52cc3de49822021-04-02T10:44:40ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2020-09-0153732743A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney diseaseYanhong Ma0Fanghao Cai1Yangyang Li2Jianghua Chen3Fei Han4Weiqiang Lin5Kidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Zhejiang Province, Hangzhou, 310003, ChinaKidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Zhejiang Province, Hangzhou, 310003, ChinaInstitute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, ChinaKidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Zhejiang Province, Hangzhou, 310003, ChinaKidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Zhejiang Province, Hangzhou, 310003, China; Corresponding author. Kidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou, 310003, China.Kidney Disease Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Institute of Nephrology, Zhejiang University, Key Laboratory of Kidney Disease Prevention and Control Technology, Zhejiang Province, Hangzhou, 310003, China; Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China; Corresponding author. The Kidney Disease Center, the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, 256 Kaixuan Road, Hangzhou, 310029, China.Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties, targetability, or the bioavailability of drugs. Thus, the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD. This review describes the current experimental research, clinical applications of NPs, the current challenges, and upcoming opportunities in the diagnosis and treatment of CKD.http://www.sciencedirect.com/science/article/pii/S2452199X20300840Chronic kidney diseaseNanoparticlesDiagnosisTreatment
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yanhong Ma Fanghao Cai Yangyang Li Jianghua Chen Fei Han Weiqiang Lin
spellingShingle	Yanhong Ma Fanghao Cai Yangyang Li Jianghua Chen Fei Han Weiqiang Lin A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease Bioactive Materials Chronic kidney disease Nanoparticles Diagnosis Treatment
author_facet	Yanhong Ma Fanghao Cai Yangyang Li Jianghua Chen Fei Han Weiqiang Lin
author_sort	Yanhong Ma
title	A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_short	A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_full	A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_fullStr	A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_full_unstemmed	A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
title_sort	review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
publisher	KeAi Communications Co., Ltd.
series	Bioactive Materials
issn	2452-199X
publishDate	2020-09-01
description	Chronic kidney disease (CKD) poses a great burden to global public health as current therapies are generally ineffective. Early detection and effective therapy are crucial for the future prevention and progression of CKD. Nanoparticles (NPs) vary by particle size, charge, shape and the density of targeting ligands and are associated with enhancement of the pharmacokinetic properties, targetability, or the bioavailability of drugs. Thus, the emergence of NPs in medicine has provided novel solutions to the potential diagnosis and treatment of CKD. This review describes the current experimental research, clinical applications of NPs, the current challenges, and upcoming opportunities in the diagnosis and treatment of CKD.
topic	Chronic kidney disease Nanoparticles Diagnosis Treatment
url	http://www.sciencedirect.com/science/article/pii/S2452199X20300840
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A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease

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