What Does PLIER Really Do?

Motivation: Our goal was to understand why the PLIER algorithm performs so well given its derivation is based on a biologically implausible assumption.Results: In spite of a non-intuitive assumption regarding the PM and MM errors made as part of the derivation for PLIER, the resulting probe level er...

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Bibliographic Details
Main Authors: Terry M.Therneau, Karla V.Ballman
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cancer Informatics
Online Access:http://la-press.com/article.php?article_id=974

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